Frequent tipster Leonid Nemirovsky shares a tip on creating new Initial Setup workspaces in AutoCAD 2010. "If for some reason Initial Setup (a new feature in 2010) is not the one you need for a particular job (for example, it was set as Civil and you need Structural settings), then open the Options window (any way you prefer), browse to the User Preferences tab, and select the Initial Setup button at the bottom left corner of the dialog box. AutoCAD will automatically create additional Initial Setup Profiles and number them. You can rename them later if you choose, and then switch from Structural Initial Setup to Civil Initial Setup and so on."
Notes from Cadalyst Tip Patrol: When AutoCAD 2010 is installed on a computer, the startup sequence will ask you a few questions about industry, drafting tools, units, etc., and will use that information to create a workspace called Initial Setup. Follow Len’s tip if you need to change this configuration for any reason. Note that some AutoCAD-based verticals — such as Map 3D — do not have this feature.